Optimus Prime is the leader of the autobots that fought against the decepticons led by Megatron on the planet of Cybertron and later traveled to Earth to continue their battle, years later upon the discovery of the shape shifting species Metalers which can infect any organism especially machine, Optimus Prime along with the Autobots and alongside the Decepticons evacuated his planet to flee to Earth to join an alliance and develop friendship with many humans, animals, as well as peaceful and friendly species of aliens and being a good friend being respectful to Spartan Joaquin, Mario, and Lindo the Echidna. He serves as a major supporting character of Super Smash Bros. Brawl Crossover.
Over the centuries ever since the 16th century (a century after the middle ages), Optimus Prime alongside the Autobots has fought against Megatron whom is allied with the Decepticons on Cybertron. He later traveled to Earth to explore the environment of the humans and later continued his battle against Megatron. After being victorious, Optimus returned to Cybertron to reside their, Optimus Prime later began hearing reports of Autobots and Decepticons being infected by hostile species attacking various areas, Optimus soon began investigating the area and soon sees hostile molecules attacking a Decepticon and then infecting it into a metal like creature. Optimus and the Autobots begin studying on the hostile substance and learn that they were once a species exterminated from an enemy faction who used a poison to destroy them and when an ancient warrior named Teridax arrived on their planet, he created a magic spell to reanimate them into a hostile shape shifting species known as Metalers and have began infesting many planets and conquering ships in which they are invading and are attacking Cybertron(since their planet is close to Cybertron during the middle ages). Optimus Prime begins to learn that the Metalers are too dangerous for the Autobots to fight, Optimus Prime decides that he and his Autobots would rather escape and flee to Earth. The Autobots go in their spacecraft and flee to Earth.